Hypertension is a common sign of which endocrine disorder?

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Hypertension, or high blood pressure, is frequently associated with Cushing syndrome. This endocrine disorder is caused by prolonged exposure to elevated levels of cortisol, a hormone produced by the adrenal glands. The excess cortisol can lead to several physiological changes in the body, including increased blood volume and enhanced sensitivity of blood vessels to constrict, both of which contribute to elevated blood pressure.

In addition, Cushing syndrome is characterized by various symptoms that stem from cortisol’s effects, such as weight gain, moon facies, and a propensity for developing metabolic abnormalities. These factors, combined with the specific hormonal imbalances in Cushing syndrome, make hypertension a common and clinically significant sign of this disorder.

Other endocrine disorders mentioned, such as Addison's disease, hypopituitarism, and diabetes insipidus, do not typically present with hypertension. Instead, Addison's disease is associated with low blood pressure due to insufficient cortisol levels, hypopituitarism can lead to various deficiencies that do not directly influence blood pressure in the same way, and diabetes insipidus primarily affects fluid balance and often results in increased thirst and urination, but not hypertension.

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